Miami → Manaus (19 nights)

Welcome to Miami and the sweep of South Beach - backdrop to every iconic Miami movie, and forefront of Latin American culture. Stroll through pastel-hued geometric buildings in the art deco district, to graffiti mural masterpieces at Wynwood Walls. Watch Latino life unfold in Little Havana - the heartbeat of this great city - where walk-up windows sell café cortadito, sweet sugarcane juice, hatuey beer and guava ice-cream. Watch passionate locals discuss politics, play dominoes and smoke cigars. Shimmy at a salsa class, shop designer boutiques and race marlin and sharks by speedboat. Then slow your pace to uncover rare and endangered species at the Everglades National Park outdoor oasis. You’ll find the Miami dream is real – and it’s not just Cuban heels that will give you a spring in your step.

The queen of the “Silver Coast”, Puerto Plata is treasured for her soaring cloud-shrouded peaks and stunning shining beaches. Once famously plundered by pirates — you too can storm the 16th-century Fortaleza San Felipe fort — now is coveted by modern-day aficionados seeking her bounty of aged rum, robust cigars, and rich chocolate. Adventurers can soar to the top of the Pico Isabel de Torres 793 mt (2,602 ft), dare to off-road to the Waterfalls of Damajagua, or kite-surf, catamaran, and zip-line over the ocean. Pro tip: save time for a buzzy beach club to chill with coconut-fused libations.

Princely Philipsburg reigns as the capital of the Dutch side of the dual-nation island of Sint Maarten/ and French Saint Martin. Lounging beside aptly named Great Bay, the seaside city weaves colourful streets lined with Dutch emporiums brimming with chocolates, cheeses and coveted luxuries. Kayak lapis-blue waters, dive amongst a kaleidoscope of reefs or gallop on horseback along shaded plantation trails. Play ‘lady luck’ in winning casinos or a round of golf beside an eternally blue sea. Every moment embraces the idea that a day in Philipsburg is royal.

In dainty Terre-de-Haute, diminutive sibling of Guadeloupe and queen of the Îles des Saintes, French charm and Caribbean culture are woven together in laid-back towns and sleepy fishing villages. High above, Fort Napoleon and Le Chameau peak are flanked by fragrant forests of fern and frangipani, overlooking picture-perfect landscapes bathed in golden sunlight and sailboats afloat on gin-clear bays.

Formed by volcanoes, St Kitts fertile soil is so rich it turns monkeys green. Trek through miles of rainforest amongst colourful wildlife to conquer the highest peak of Mount Liamuiga so you can peer into the mile-wide crater, or bravely descend to sniff the sulphur. Experience a train ride, sailing trip, cooking class, sky safari zip-line, or creative batik fabric workshops. Visit sugarcane plantations, the Narrows between St Kitts and Nevis and the UNESCO Brimstone Hill Fortress for spectacular views of neighbouring islands. You’ll find this special island small in size yet tall in standing, as well as big on charm.

Explore the oldest US city for a dose of Caribbean history, slice of Spanish culture and twist of American dream. Roam historic Old San Juan alleyways to glimpse centuries-old forts and colourful colonial buildings. Learn how to move, as locals sashay out the salsa to rhythmic reggae beats. Shop the boho streets or glamorous boutiques for artisan goods, decadent designers and hand-rolled cigars. Experience world-class surfing, explore a tropical rainforest, attend a private rum cocktail tasting and polish off empanadas. Then retire to one of the beautiful beaches to soak up crystal clear waters and, perhaps, one last rum cocktail.

Mingle amongst other discerning guests on this French isle that exudes relaxed glamour. Wander along secluded beaches, harbourside Creole huts, drop into bohemian bars and snorkel gently through warm turquoise waters. Visit La Tourmente, the peaceful salt ponds and admire uninterrupted views on a local boat trip. And as you sip your second (or third) glass of champagne to the lull of the gentle waves, it might be time to learn the French for "paradise found".

Embrace Martinique’s natural joie de vivre. Volcanic in origin, Gallic in heritage and Creole at heart; explore old sugar plantations, premium rum distilleries, cocoa farms and St Pierre ruins at the foothills of the still smouldering Mont Pelée. Chase the Saut du Gendarme waterfall, explore the 10 million-year-old Caravelle peninsula, roam northern beach dusky sands and visit Le Carbet made famous by the artist Gauguin. And as you slow down to contemplate the sweet concoction of the national punch, you’ll understand why the Creole and French blend makes Martinique so magical.

Gently breeze into the vibrant capital of Barbados. Steeped in fascinating history, with architecture to match, uncover the wonderfully laid-back West Indian ambiance. Embrace the slow Bajan rhythm of this welcoming island; surf, snorkel and try spotting turtles in balmy azure waters. Explore subterranean Harrison’s Cave, Jacobean St Nicholas Abbey and zipline high above bountiful tropical flora. Then return to restore on pastel pink sands at palm-studded beaches, where you’ll discover cocktail hour is endless, and measures of rum are copious.

Please note that the call to Macapá is a technical call required for clearance by the Brazilian authorities. Guests will not be able to disembark during this time. The clearance process includes a safety inspection, health inspection, and immigration formalities. Depending on the complexity, this may take several hours.

Panoramas are big and population is sparse in this small settlement where the Amazon River meets the Rio da Valeria. Revel in a simple village lifestyle that’s been followed by the Amerindians for centuries. Follow footpaths into lush rainforest, paddle canoes into remote tributaries, and share joyful moments with loving communities who thrive on simplicity and meaningful connections.

The beating heart of the Brazilian rainforest. This bustling frontier town emanates a verdigris grandeur, a throwback to the rubber boom gone by, illustrated best by the Belle Epoque opera house, with its marble halls and 198 Murano glass chandeliers. Drift away to the Philharmonic strains of Verdi or Mozart under frescoed ceilings in the midst of the steamy jungle. Outside, the inky Rio Negro meets but doesn’t merge with the more muddied Rio Solimoes, and pink dolphins, manatees and river otters ply the wide and winding waterways, the banks and jungle trails scattered with waterfalls, wild orchids, spider monkeys and jaguars.

The beating heart of the Brazilian rainforest. This bustling frontier town emanates a verdigris grandeur, a throwback to the rubber boom gone by, illustrated best by the Belle Epoque opera house, with its marble halls and 198 Murano glass chandeliers. Drift away to the Philharmonic strains of Verdi or Mozart under frescoed ceilings in the midst of the steamy jungle. Outside, the inky Rio Negro meets but doesn’t merge with the more muddied Rio Solimoes, and pink dolphins, manatees and river otters ply the wide and winding waterways, the banks and jungle trails scattered with waterfalls, wild orchids, spider monkeys and jaguars.