Civitavecchia (Rome) → Piraeus (Athens) (20 nights)

There’s more to Rome than its ancient architecture. The Eternal City is home to a seemingly endless array of hidden gems. The artistic-minded can enjoy fashion aristocracy, street art, vespa jaunts to The Appian Way and toss coins into fountains. Or you can stroll by appointment to Michelangelo’s Sistine Chapel and the Pope’s private quarters at the Vatican. Explore the historic ruins of The Colosseum, Caravaggio churches, the Spanish Steps and The Pantheon. Learn how to make pasta the true Italian way, hunt truffles, nibble gelato, sip coffee and sink into a 3000 year old pool for a wellness experience. An ode to homespun pasta at a Renaissance piazza. When in Rome, fusing old with new makes it simple to indulge in whatever you like.

Plunge into Tuscany’s capital of culture. Once casa to legendary Michelangelo, Florence now shelters some of the Renaissance’s greatest masterpieces. Immerse in the relics of antiquity; catch a glimpse of the heavens in the famous Uffizi gallery, visit the iconic terracotta-tiled Duomo and step into an oasis of sculptured serenity at Giardino di Boboli to forget the world beyond its leafy walls exists. And as the sun sets over the Ponte Vecchio, relax in an elegant terrazzo with a rich refined Tuscan red, and reflect on the city’s Medici dynasty - Hurry Slowly.

Yacht-studded seas and palm trees form Cannes’ iconic Riviera backdrop. Yet inside are a swish marina, perfumed forests, casinos, iconic boutiques, cinematic heritage, and supermodels. Stroll ancient narrow winding streets of the hilly Le Suquet and feel its medieval past, shop fashion labels on palm-flanked La Croisette, slide into sleek Michelin-starred restaurants, and lie low in plush beach clubs where glittering sea views take central stage. Peace seekers may ferry to leafy island of Saint-Honorat and the 500-year-old monastery. Take a spin along the Cote d’Azur to moneyed Monaco or glitzy St Tropez. Cannes has curves in all the right places – the oh so French social hub that defines seaside glamour.

Corsica’s capital, a 16th-century citadel cradled by mountains on the island’s west coast, could take its magnetic moniker from its founder, the Greek hero Ajax, or from the word adjaccium, Roman for “place to rest”. This is Napoleon’s birthplace, so beeline the old town’s charming narrow streets to Maison Bonaparte, the family home and now a museum, and Baroque cathedral where he was baptised in the marble font. Meander markets popular with foodies seeking local winemakers, olive oil, chestnuts and cheeses, and kick back on white sands in the beautiful Bay of Ajaccio with views of the Genoese tower on the Parata Peninsula and rust-coloured Sanguinaire islands beyond.

Beckon the buzz of a small UNESCO-listed island; proud of producing its own cheese, wine and rather distinguished gin. Sink into a lemon-scented laidback lifestyle that reflects elegant Georgian architecture, Spain’s oldest opera house, history, art and a monastery-based museum. Off glittering turquoise shores, visit the Royal Naval hospital, shop for world-renowned shoes, amble amongst butterflies up coastal paths and rest for tapas in harbour-side tavernas. Celebrated yet discreet – unhurried Menorca is the low-key location to go and not to be seen.

Enjoy the epitome of Spanish charm. Slowly discover Andalusian riches to reveal Picasso’s birthplace, the Alhambra in Granada, Mezquita in Cordoba and the Ronda valley. Explore ancient heritage sites, dance the flamenco, dare to hike the Caminito del Rey trail and delve into white villages sprinkled amongst mango groves and avocado orchards. Sip cocktails by day and sangria by night. And as you watch the sun slip down, reflect upon this gateway of delights.

Enjoy the epitome of Spanish charm. Slowly discover Andalusian riches to reveal Picasso’s birthplace, the Alhambra in Granada, Mezquita in Cordoba and the Ronda valley. Explore ancient heritage sites, dance the flamenco, dare to hike the Caminito del Rey trail and delve into white villages sprinkled amongst mango groves and avocado orchards. Sip cocktails by day and sangria by night. And as you watch the sun slip down, reflect upon this gateway of delights.

Blue-domed cathedrals, cobbled alleyways and leafy plazas shaded by giant Ficus trees set the scene for magical moments in Alicante, gateway to Costa Blanca beaches, jagged mountains and medieval villages. Wander through the narrow streets of El Barrio and gorge on turrón and tapas, then climb the steps to timeless Santa Cruz, where whitewashed houses, flecked with colourful pots, cling to steep staircases on the flanks of Mount Benacantil. High above lies the mighty Castel de la Santa Bàrbara, a 1,000-year-old sandstone citadel commanding spectacular views of the glittering Mediterranean and the tile mosaic of palm-fringed Explanada de España on the harbourside.

Breathe in the cultural heart of Catalan; an elegant blend of high energy and undisturbed tradition. Muse over the origins of captivating Gaudi architecture within the enchanting labyrinth that is the Gothic Quarter. Savour the flavours of fresh tapas and crisp cava in breezy plazas, tranquil terraces and coveted cafés, or glide down to a shimmering beach club to unwind. Imagine a visit to peaceful Passeig de Gracia, where modernist buildings merge to showcase iconic global labels. And, as dusk falls, prepare for urban action and swing by the lively bohemian bars to fiesta on the leafy stretch of La Rambla. If you’re serious about style, this colourful city provides plenty to celebrate.

Supremely situated between the Cinque Terra and Pisa with fabulous Florence and lesser-travelled Portovenere in between, La Spezia gives you space to explore the beauty of Liguria. Go ashore and surrender to the region’s culinary artistry in cosy trattorias or delve into its illustrious naval history. In every direction, UNESCO sites abound the five colourful coastal villages of Monterosso, Vernazza, Corniglia, Manarola, and Riomaggiore; venture to Pisa’s leaning tower and Piazza dei Miracoli; hop a boat to more quiet yet still colourful Portovenere’s village with medieval cliff-topped Doria Castle. Stay close or venture an hour out, either way, you will love illustrious La Spezia.

There’s more to Rome than its ancient architecture. The Eternal City is home to a seemingly endless array of hidden gems. The artistic-minded can enjoy fashion aristocracy, street art, vespa jaunts to The Appian Way and toss coins into fountains. Or you can stroll by appointment to Michelangelo’s Sistine Chapel and the Pope’s private quarters at the Vatican. Explore the historic ruins of The Colosseum, Caravaggio churches, the Spanish Steps and The Pantheon. Learn how to make pasta the true Italian way, hunt truffles, nibble gelato, sip coffee and sink into a 3000 year old pool for a wellness experience. An ode to homespun pasta at a Renaissance piazza. When in Rome, fusing old with new makes it simple to indulge in whatever you like.

Pitched between mighty Mount Vesuvius and the volcanic calderas of Phlegraean Fields, history is revealed around every corner of Naples, cradle of Italian culture. Baroque churches, Italian-Renaissance palazzi and Neoclassical opera houses leave you breathless, so ride the funicular up to the top of Castel Sant’Elmo for dreamy views of the Bay of Naples and Sorrento Peninsula beyond, gateway to the spectacular Amalfi Coast. Beneath the cobblestone streets lies another Naples, a warren of subterranean tunnels hewn by legions of Roman and Greek settlers. Linger longer to visit the ancient ruins of Pompeii and Herculaneum, buried under the wrath of Mount Vesuvius, or hop over to the idyllic Island of Capri.

Dip in a Mediterranean mass of rich history, cuisine and abundant nature. Wander through historic cities, Roman sites, Greek temples and expansive vineyards. Skirt around simmering Mount Etna’s fertile lava lands, survey Grecian archaeology inland at Valle Dei Templi Grecian, seek out tumbled ruins at sea-facing Selinunte and drop in to Casale to admire ornate mosaics. Attend an Etna Rosso wine tasting, head for peace at the nature reserve and liven up at the Baroque old town of Sciacca. And for a final taste of Sicily, feast on olive oil drenched pasta - you won’t leave this honey-hued region unfulfilled.

Unearth the Med’s master of restoration and renovation behind honey-hued Valetta’s fortified walls. Strewn with a mass of well-preserved history - head back in time to hand-carved shelters, a maze of subterranean tombs and stone-age temples. Discover war secrets beneath the limestone streets, skim the Grand Harbour aboard a dghajsa, step into state history and get your fill of art and Fat Ladies in museums. But it’s not all ancient history - watch buzzing bars spill out onto limestone alleys, treat yourself to Michelin-starred Maltese cuisine, neighbourhood watch and dive over wrecks. Malta may be Europe’s tiniest capital, but she packs a might punch.

If you start early, you’ll have Mykonos to yourself. Stroll narrow streets famous for Cycladic architecture and getting lost; white-washed cubed buildings, alluring boutiques, orthodox churches and traditional windmills. Join glitterati guests at elegant events on iconic beaches, sink into saltwater pools, tour vineyards and dance at bars where beats evolve in tempo (and volume). When the heat of the day dies down, drop into the sacred isle of Delos to explore remarkable ruins; amphitheatres, temples, public squares, marketplaces and shrines to Greek Gods. Take a table in central Chora for perfectly-cooked, local dishes with generous views; mounds of flaky filo, Greek salads, halloumi and sea urchin, washed down with freddo. When the sun sets, head for a signature sundowner with views across the ocean. After dark, follow the fun to legendary bars and clubs. Progressive and profoundly beautiful.

A tiny island with a big reputation. Voyage to this discreet island where few go. Famed for being the discerning guests’ paradise; sun-kissed beaches, clear waters shielded by protective coves and undeniably warm local hospitality. Classically Greek with beautiful, mountainous views of perfectly positioned white houses dotted high into the hills. Known as the Land of Legends, St John was said to have written his Book of Revelations here. Quiet but with a powerful energy, you’ll understand why this island was named "Letois", after the goddess and huntress of deer, Artemis, daughter of Leto. It was believed that Patmos came into existence thanks to her divine intervention.

Dreamily sail into Santorini when others leave. Romantic, exuberant and pure; roam one of the world’s most enchanting islands as you enjoy breathtaking scenery, rock-set whitewashed houses, paved paths, sugar white sand, black beaches and terracotta cliffs. Experience the many geological and architectural delights; blue-domed churches, an active volcano, excavate with experts and cover the caldera between cliff-hanging Oia and Fira. Glide through sapphire seas in a catamaran, taste local wine, eat freshly-caught seafood, break plates and shop elegant boutiques. Then settle in for a slow moonlit dinner high on a hilltop, just in time for the world-famous sunset.

Athenians don’t live in the past. Ahead of its time, Athens exudes glamour and a sense of possibility - housing galleries, gelaterias, bijoux boutiques alongside a plethora of museums. And you can’t help but marvel at the archaeological wonders of the Acropolis and the Parthenon. Stroll through vibrant streets and markets, dance at buzzing bouzoukia, sing along in tavernas. At night, head to the harbour, where dimly lit bars serve the local ice cold beer. And, as you inhale the salty air and watch Greek fishing boats peacefully depart for their catch, reflect on this ancient city's progressive attitude.